Christian P. Petersen
Regeneration is widespread in nature but poorly understood. Regenerating animals are confronted with unique challenges that defy explanation—production of fully differentiated structures starting from an adult rather than embryonic context, integration of newly regenerated and previously existing tissues, and specification of the identity of regenerating tissues. What molecular and cellular processes do regenerating animals use to solve these problems?
Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration. Bonar NA and Petersen CP. Development. 2017 March 1;144(5):784-794.
The NuRD complex component p66 suppresses photoreceptor neuron regeneration in planarians. Vásquez-Doorman C and Petersen CP. Regeneration. 2016 August 18;3(3):168-178.
Wnt, Ptk7, and FGFRL expression gradients control trunk positional identity in planarian regeneration. Lander R and Petersen CP. eLife. 2016 April 13;5:e12850.
Wnt/Notum spatial feedback inhibition controls neoblast differentiation to regulate reversible growth of the planarian brain. Hill EM and Petersen CP. Development. 2015 December 15;142(24):4217-4229.
teashirt is required for head-versus-tail regeneration polarity in planarians. Owen JH, Wagner DE, Chen C-C, Petersen CP, and Reddien PW. Development. 2015 March 15;142(6):1062-1072.
Planarian Resistance to Blades and Bugs. Petersen CP. Cell Host & Microbe. 2014 September 10;16(3):271-272.
zic-1 Expression in Planarian Neoblasts after Injury Controls Anterior Pole Regeneration. Vásquez-Doorman C and Petersen CP. PLoS Genetics. 2014 July 3;10(7):e1004452.
Polarized notum Activation at Wounds Inhibits Wnt Function to Promote Planarian Head Regeneration. Petersen CP and Reddien PW. Science. 2011 May 13;332(6031):852-855.
Wnt Signaling and the Polarity of the Primary Body Axis. Petersen CP and Reddien PW. Cell. 2009 December 11;139(6):1056-1068.
A wound-induced Wnt expression program controls planarian regeneration polarity. Petersen CP and Reddien PW. PNAS. 2009 October 6;106(40):17061-17066.
Smed-βcatenin-1 Is Required for Anteroposterior Blastema Polarity in Planarian Regeneration. Petersen CP and Reddien PW. Science. 2008 January 18;319(5861):327-330.
14-3-3σ controls mitotic translation to facilitate cytokinesis. Wilker EW, van Vugt MATM, Artim SC, Huang PH, Petersen CP, Reinhardt HC, Feng Y, Sharp PA, Sonenberg N, White FM, and Yaffe MB. Nature. 2007 March 15;446(7133):329-332.
Short RNAs Repress Translation after Initiation in Mammalian Cells. Petersen CP, Bordeleau M-E, Pelletier J, and Sharp PA. Molecular Cell. 2006 February 17;21(4):533-542.
View all publications by Christian P. Petersen listed in the National Library of Medicine (PubMed). Current and former IBiS students in blue.