Thomas J. Meade Bioinorganic coordination chemistry, biological molecular imaging, transcription factor inhibitors, electronic biosensors

Research Interests

The Meade Lab research focuses on inorganic coordination chemistry for the study of molecular imaging of in vivo gene expression and intracellular messengers, transition metal enzyme inhibitors, and electronic biosensors. The design, synthesis and physical properties of transition metal and lanthanide coordination complexes are the foundation of our research.

Selected Publications

Synthesis and evaluation of MR probes for targeted-reporter imaging. Verma KD, Massing JO, Kamper SG, Carney CE, MacRenaris KW, Basilion JP, and Meade TJ. Chemical Science. 2017 August 1;8:5764-5768.

Gd(III)-Gold Nanoconjugates Provide Remarkable Cell Labeling for High Field Magnetic Resonance ImagingRammohan N, Holbrook RJ, Rotz MW, MacRenaris KW, Preslar AT, Carney CE, Reichova V, and Meade TJ. Bioconjugate Chemistry. 2017 January 18;28(1):153-160.

Gd(III)-Dithiolane Gold Nanoparticles for T1-Weighted Magnetic Resonance Imaging of the Pancreas. Holbrook RJ, Rammohan N, Rotz MW, MacRenaris KW, Preslar AT, and Meade TJ. Nano Letters. 2016 May 11;16(5):3202-3209.

Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast AgentMacRenaris KW, Ma Z, Krueger RL, Carney CE, and Meade TJ. Bioconjugate Chemistry. 2016 February 17;27(2):465-473.

Targeted Inhibition of Snail Activity in Breast Cancer Cells by Using a CoIII-Ebox ConjugateVistain LF, Yamamoto N, Rathore R, Cha P, and Meade TJ. ChemBioChem. 2015 September 21;16(14):2065-2072.

View all publications by Thomas J. Meade listed in the National Library of Medicine (PubMed). Current and former IBiS students in blue.